Aclasta & Zometa Infusions
Hunter Blood Group provides Aclasta and Zometa infusions at our purpose-built clinic in Newcastle West. Both treatments use zoledronic acid -- a bisphosphonate that strengthens bone -- but at different doses for different conditions. Aclasta is used for osteoporosis, while Zometa prevents skeletal complications in patients with myeloma or breast cancer. All infusions are administered by experienced haematology nurses under specialist haematologist supervision for patients aged 16 years and over.
Aclasta vs Zometa: what is the difference?
Aclasta and Zometa are both brand names for zoledronic acid, but they are prescribed at different doses and frequencies for different medical conditions. Your referring doctor will specify which treatment you need.
| Feature | Aclasta | Zometa |
|---|---|---|
| Active ingredient | Zoledronic acid 5 mg | Zoledronic acid 4 mg |
| Primary indication | Osteoporosis treatment and prevention | Skeletal complications of myeloma and breast cancer |
| Frequency | Once yearly | Every 3 to 4 weeks |
| Infusion duration | At least 15 minutes + observation | At least 15 minutes + observation |
| PBS funding | PBS listed for eligible patients | PBS listed for eligible patients |
Who is zoledronic acid infusion for?
Aclasta (osteoporosis)
- Post-menopausal osteoporosis
- Osteoporosis in men
- Corticosteroid-induced osteoporosis
- Paget's disease of bone
- Patients who cannot tolerate oral bisphosphonates
Zometa (cancer-related)
- Multiple myeloma with bone involvement
- Breast cancer with bone metastases
- Prevention of skeletal-related events (fractures, spinal cord compression)
- Hypercalcaemia of malignancy
What to expect: the infusion process
- 1 Referral -- Your GP or specialist sends a referral to Hunter Blood Group. Our haematologists review the referral and confirm the treatment plan.
- 2 Prescription -- You obtain your zoledronic acid prescription from the pharmacy. PBS funding is available in certain situations. You may also receive a prescription from our doctors after referral review.
- 3 Booking -- Our team schedules your infusion appointment at our Hunter Street rooms in Newcastle West. If you have difficult veins, please mention this at booking.
- 4 Infusion day -- Arrive at your appointment, bring your medication from the pharmacy. The infusion takes at least 15 minutes, followed by a short observation period.
- 5 Aftercare -- Stay well hydrated after your infusion. Mild flu-like symptoms may occur for 24 to 48 hours after the first dose. Your GP will be sent a summary of your treatment.
Duration and frequency
Each infusion takes at least 15 minutes plus a post-infusion observation period. Aclasta is typically given once per year. Zometa is given every 3 to 4 weeks as part of an ongoing treatment plan. Total time at the clinic is usually 30 to 60 minutes including check-in and observation.
Preparation
- Bring your medication from the pharmacy to your appointment
- Drink plenty of water before and after the infusion
- Mention difficult veins when booking so our nurses can plan accordingly
- Recent blood test results may be required (kidney function and calcium levels)
Fees for Aclasta and Zometa infusions
The following fees apply to the administration of zoledronic acid infusions during the first 12 months of treatment. Fees do not include the cost of the medication itself, which is dispensed separately by your pharmacy.
| Item | Amount |
|---|---|
| Infusion administration fee | $231.90 |
| Medicare rebate | -$151.90 |
| Out-of-pocket gap | $80.00 |
| Safety net gap (if threshold reached) | $16.00 |
Fees shown are for the first 12 months. Pharmacy dispensing fees for zoledronic acid are charged separately by your pharmacy and are not included in the above. The Medicare Safety Net may further reduce your out-of-pocket cost once annual thresholds are met. Visit our fees page for full details on billing, safety net entitlements, and payment options.
Payment options
We accept credit card, debit card, cash, and Afterpay. With Afterpay you can pay for your infusion gap fees in four interest-free instalments.
Prescription and PBS information
How to obtain your medication
Zoledronic acid (Aclasta or Zometa) is a prescription medication that you bring to your infusion appointment. You can obtain your prescription in one of two ways:
- From your referring doctor (GP or specialist)
- From our haematologists, after reviewing your referral
PBS funding
Zoledronic acid is listed on the Pharmaceutical Benefits Scheme (PBS) for eligible patients, which significantly reduces the pharmacy cost. PBS funding is available only in specific clinical situations -- your doctor will confirm your eligibility.
Most community pharmacies can order zoledronic acid, but it may not be held in stock. Let your pharmacist know in advance so they can order it in time for your appointment.
How to refer for an Aclasta or Zometa infusion
A referral from a GP or specialist is required for all zoledronic acid infusions. You can submit a referral using any of the following methods:
Age requirement
Hunter Blood Group provides infusions for adults aged 16 years and over only. Patients under 16 should be referred to a paediatric specialist.
Frequently asked questions
What is the difference between Aclasta and Zometa?
Aclasta and Zometa both contain the same active ingredient, zoledronic acid, but are prescribed for different conditions. Aclasta (5 mg) is a once-yearly infusion for osteoporosis, while Zometa (4 mg) is given every 3 to 4 weeks for skeletal complications of myeloma or breast cancer. Your doctor will prescribe the appropriate formulation for your condition.
Do I need a referral for an Aclasta or Zometa infusion?
Yes. A referral from a GP or specialist is required for all zoledronic acid infusions at Hunter Blood Group. This ensures we have the clinical information needed for safe treatment and that you receive your full Medicare rebate.
How long does an Aclasta or Zometa infusion take?
The infusion itself takes at least 15 minutes. Including check-in, cannulation, and a post-infusion observation period, you should expect to be at the clinic for 30 to 60 minutes in total.
What are the side effects of zoledronic acid?
The most common side effect is a flu-like reaction (fever, muscle aches, headache) which typically occurs within 24 to 48 hours of the first infusion and resolves on its own. This reaction is less common with subsequent infusions. Paracetamol can help manage symptoms. Serious side effects are rare. Your haematologist will discuss risks and benefits before treatment.
How much does an Aclasta or Zometa infusion cost in Newcastle?
The infusion administration fee is $231.90, with a Medicare rebate of $151.90, leaving an out-of-pocket gap of $80 (or $16 if you have reached the Medicare Safety Net threshold). This does not include the cost of the medication itself, which is dispensed by your pharmacy and may be PBS-subsidised. Afterpay is available for the gap fee.
Need an Aclasta or Zometa infusion?
Submit a referral or call 02 4092 7788.